6 Best Restaurants in Denver, Colorado

This dining room in Hotel Monaco is filled with fresh flowers and windows that let in natural light, making the space cheerful and bright. The focus is on true, multilayered Italian cuisine, such as grilled flatbread topped with cheese, prosciutto, truffle oil, and balsamic vinegar; or risotto made with an ever-changing and ever-pleasing variety of cheeses and fresh produce. The breads are baked in-house. The superior service and accommodating staff make for a pleasant dining experience. The large, roomy bar is available for dining, too.

If it's martinis and jazz you're after, come to this casually elegant space (larger and snazzier after a move to the historic Baur's Building), which features comfort foods with a twist and small plates. Live music most nights makes this a laid-back spot. The cocktail roster, printed inside old jazz albums, is one of the most intricate around, and the Sunday jazz brunch swings.

Greek immigrant Sam Armatas opened his first eatery in Denver in 1927, and his three sons use the same recipes their father did in their updated version of his all-American diner, from the famous red and green chilis to the Coney Island–style hot dogs and creamy rice pudding. The retro diner resembles a fancy Denny's, and the bar is crowded with theatergoers and hipsters after dark. Good luck choosing: the menu is 12 pages long, with Greek and Mexican favorites as well as diner classics. The chunky mashed potatoes rule, as do the pie-based milkshakes, and breakfast, which is served all day, comes fast.

Originally a food truck, the name of this taqueria showcases exactly what it specializes in: queso a la plancha tacos and seared ahi tuna tacos, with house-made salsas and tangy margaritas. Get to know your fellow diners at the communal tables or the long bar, or sit on the patio that opens from the dining area through the garage door. There's a second location in City Park.

A basic contemporary American menu offers classics done well at the Nickel, the restaurant located in the Hotel Teatro. Enjoy a top-notch burger, an entrée-sized salad, or Mediterranean-style salmon, all while kicking back in sumptuously upholstered chairs. Breakfast and weekend brunch offer some unique options like carrot cake pancakes. The room takes terrific advantage of the natural light that floods the space, making the ambience feel impressive and special. Rooftop bees provide in-house honey.

Holistic health guru Dr. Andrew Weil has opened restaurants in select locations in 17 states, and this venture in Cherry Creek, where his intensive focus is on anti-inflammatory preparations and antioxidant ingredients prepared with an international flair, has met with great success. Don't expect all-vegetarian, however; the menu offers plenty of meat, particularly lean bison and turkey, as well as fish, tempeh, and other meat substitutes. Trendy cocktails—cucumber margarita or blueberry acai mojito, for example—and natural sodas add to the appeal for the younger crowds that flock to the communal tables for small plates and thin-crust pizzas. The kids' menu is impressively healthy and appealing with its mini grass-fed burger and chicken teriyaki bowl.