The park's western gateway is the most convenient entrance for travelers coming from Southwest Florida. From Naples, take U.S./Highway 41 east for 37 miles, and turn right onto State Road 29. To reach the Gulf Coast entrance from Miami, take U.S./Highway 41 (Tamiami Trail) west for about 90 miles, turn left (south) onto State Road 29, and travel another 3 miles through Everglades City to the Gulf Coast Ranger Station.
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